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Senolytic combination treatment is more potent than single drugs in reducing inflammatory and senescence burden in cells from painful degenerating IVDs

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Pharmaceutics, 17(3), 385

These cells not only retained mitotic capacity, but also maintained a more youthful morphology and gene expression profile, indicating real preservation of cellular youth

it modulates the expression of over 4,000 human genes, including those responsible for inflammation control, DNA repair, collagen and elastin synthesis, antioxidant defense, and stem cell activity